CYP2R1

CYP2R1

The CYP2R1 Gene- The Cytochrome P450 2R1 genes enzyme converts cholecalciferol into calcifediol in the liver. CYP2R1 catalyzes vitamin D from our diet or skin into calcifediol that circulates in our blood.

Calcifediol- typically converts to calcitriol (bioactive vitamin D) in the kidneys to binds with vitamin D receptors (VDR).

Testing- calcifediol is monitored by a blood test as for vitamin D status.